发表论文情况：

(*第一作者，#通迅作者)

2019

39. LLiu, W Tao, B Lin, C Li, X Zheng, S Zhu^#,W Jiang^#, R Zhou^#.2019. Commensal viruses maintain the homeostasis of intestinalintraepithelial lymphocytes via non-canonical RIG-I signaling. Nat Immunol.s41590-019-0513-z(^#co-corresponding author)(IF=20)

38. H Ma*, W Tao*, and S Zhu^#. 2019. T Lymphocytes in Intestinal Mucosa: Defense and Tolerance. Cell Mol Immunol. (2019) 16:216–224. (^#corresponding author; Invited review)(IF=8)

37.W Zhang and S Zhu^#. 2019.Gut metabolites: make orphans adopted. Precision Clinical Medicine.doi:10.1093/pcmedi/pbz012. (^#corresponding author)

36. A Wang*,GZhang*, W Tao*,S Zhu^#. 2019. The immune response towards enteric virus in inflammatory bowel disease. 2019. Chin J Inflamm Bowel Dis.January 2019, Vol.3,No.1(^#corresponding author; Invited review)

35. W Tao*,S Zhu^#. 2019. Gut virome in health and disease. Journal of Biology, 2019, 36(6): 1-.(^#corresponding author; Invited review)

34. J Wang, MF. Sanmamed, I Datar, T Su, L Ji, J Sun, L Chen, Y Chen, G Zhu, L Zheng, T Zhou, T Badri, S Yao, S Zhu, A Boto, M Sznol, I Melero, DA. Vignali, K Schalper and L Chen^#. 2018. Fibrinogen-like protein 1 is a major ligand of LAG-3 for T-cell suppression and the evasion of tumor immunity. Cell. 176, 1–14.doi:org/10.1016/j.cell.2018.11.010. (IF=32)

33. LYang*, S Zhu, P Wang^# et al. 2019. The STING-MSR1 Axis Controls RNA Virus Infection Through Noncanonical Autophagy. SSRN Electronic Journal.

2018

32. S Ding, S Zhu, L Ren, N Feng, X Ge, B Li, RA Flavell, HB Greenberg^#. 2018. Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells. Elife. 2018 Nov 21;7. pii: e39494. doi: 10.7554/eLife.39494.(IF=8)

31. L Wu, J Cao, WL Cai, SM Lang, JR Horton, DJ Jansen, ZZ Liu, JF Chen, M Zhang, BT Mott, K Pohida, G Rai, SC Kales, MJ Henderson, X Hu, A Jadhav, DJ Maloney, A Simeonov, S Zhu, A Iwasaki, MD Hall, X Cheng, GS. Shadel, Q Yan^#. 2018. KDM5 histone demethylases repress immune response via suppression of STING. Plos Biology. 2018 Aug 6;16(8):e2006134. doi: 10.1371/journal.pbio.2006134.(IF=9)

30. J Tong, G Cao, T Zhang, E Sefik, M AmezcuaVesely, J Broughton, S Zhu, H Li, B Li, Lei Chen, H Chang, B Su, R Flavell^# & HB Li^#. 2018. m6A mRNA methylation sustains Treg suppressive functions. Cell Research. doi:10.1038/cr.2018.7(IF=15)

2017

29. Zhu S*, Ding S*, Wang P, Wang G, Lei X, Palm N, Pan W, Zheng Y, Feng N, Lu J, Shan L, Abraham C, Fikrig E, Greenberg H^#, Flavell R^#. Nlrp9b recognizes and restricts rotavirus infection in intestinal epithelial cells. 2017. Nature. doi:10.1038/nature22967. (Comment in Nature, doi:10.1038/nature23090, Comment in Nat Rev Gastroenterol Hepatol. doi:10.1038/nrgastro.2017.94.Research highlight in Cell Research, doi: 10.1038/cr.2017.93, Evaluated by Faculty of 1000 Biology, *co-first author).(IF=42)

28. Li, H.*, J. Tong*, S. Zhu*, P. Batista, J.Zhao, W. Bailis, Y. Yang, G. Wang, Y. Chen, Y. Kluger, Howard Y. Chang, Zhinan Yin^#, Richard A. Flavell^#. 2017. m6A mRNA methylation controls T cell homeostasis by targeting IL-7/STAT5/SOCS pathway. Nature. doi:10.1038/nature23450. (Comment in Immunol Cell Biol. 2017.*co-first author)(IF=42)

27. Pan W, Zhu S, K Qu, K Meeth, J Cheng, K He, H Ma, Y Liao, X Wen, C Roden, Z Tobiasova, Z Wei, J Zhao, J Liu, J Zheng, B Guo, M Bosenberg, R Flavell, J Lu^#. 2017. Tet2 sustains the immunosuppressive function of myeloid cells and promotes melanoma growth. Immunity. 2017, doi: 10.1016/j.immuni.2017.07.020.(IF=24)

26. Yu H, Borsotti C, Schickel JN, Zhu S, Strowig T, Eynon EE, Frleta D, Gurer C, Murphy AJ, Yancopoulos GD, Meffre E, Manz MG, Flavell RA^#. 2017. A novel humanized mouse model with significant improvement of class- switched, antigen-specific antibody production. Blood.  doi: 10.1182/blood-2016-04-709584.(IF=12)

25. H Yu, N Gagliani, H Ishigame, S Huber, S Zhu, E Esplugues, K Herold, L Wen, R Flavell^#. 2017. Intestinal type 1 regulatory T cells migrate to periphery to suppress diabetogenic T cells and prevent diabetes development. Proceedings of the National Academy of Sciences, doi: 10.1073/pnas.1705599114. (IF=10)

2016

24. Hu B, Jin C, Li HB, Tong J, Ouyang X, Cetinbas NM, Zhu S, Strowig T, Lam FC, Zhao C, Henao-Mejia J, Yilmaz O, Fitzgerald KA, Eisenbarth SC, Elinav E, Flavell RA^#. 2016. The DNA Sensing Aim2 Inflammasome Controls Radiation Induced Cell death and Tissue Injury. Science. 2016 Nov 11;354(6313):765-768.(IF=41)

23. Shu Zhu, Geng Wang, Xuqiu Lei, Richard A. Flavell^#. 2016. Mex3B, a coreceptor to present dsRNA to TLR3. Cell Research. 26(4):391-2. doi: 10.1038/cr.2016.29.(IF=15)

22. Cheng J, Roden CA, Pan W, Zhu S, Baccei A, Pan X, Jiang T, Kluger Y, Weissman SM, Guo S, Flavell RA, Ding Y, Lu J^#. 2016. A Molecular Chipper Technology for CRISPR sgRNA Library Generation and Functional Mapping of Noncoding Regions. Nature Communication. 7:11178. doi: 10.1038/ncomms11178.(IF=12)

2015

21. Wang P*, Zhu S*, Yang L, Cui S, Pan W, Jackson CelR, Zheng Y, Rongvaux A, Sun Q, Yang G, Gao S, Lin R, You F, Flavell R^#, Fikrig E^#. 2015. Nlrp6 regulates intestinal antiviral innate immunity. Science. 10.1126/science.aab3145. (Comment in Science Signaling (2015) DOI: 10.1126/scisignal.aad8628, *co-first author, #co-corresponding author)(IF=41)

20. Pan W*, Zhu S*, Dai D, Liu Z, Li D, Li B, Gagliani N, Zheng Y,.. Qian Y, Chen Y, Fang J, Herbst R, Richman L, Jallal B, Harley J, Flavell R, Yao Y^# and Shen N^#. 2015. MiR-125a targets effector programs to stabilize Treg mediated immune homeostasis and controls autoimmunity. Nature Communication. DOI: 10.1038/ncomms8096. (*co-first author)(IF=12)

19. Song X, Dai D, He X, Zhu S, Yao Y, Gao H, Wang J, Qu F, Qiu J, Wang H, Li X, Shen N, Qian Y^#. 2015. Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage. Immunity. doi:10.1016/j.immuni.2015.06.024. (IF=24)

18. W Pan, S Zhu, D Dai, J Harley, N Shen^#. 2015. T cell transfer Model of Colitis. Bio-protocol. 10.21769/BioProtoc.1862

2014

17. Zhu S, Li HB, Flavell RA^#. 2014. Resemble and Inhibit: when RLR meets TGF-b. Molecular Cell. Dec 18;56(6):719-20. doi:10.1016/j.molcel.2014.12.010. (IF=14)

16. Zhu S, Jackson R, Flavell RA^#. 2014. The lock-washer: a reconciliation of the RIG-I activation models. Cell Research.10.1038/cr.2014.5. (IF=15)

15. Marcel R. de Zoete*, Noah W. Palm*, Shu Zhu*, Richard A. Flavell^#. 2014. Inflammasomes. Cold Spring Haber Perspectives in Biology. Oct 16;6(12):a016287. doi: 10.1101/cshperspect.a016287 (*co-first author)(IF=12)

14. Song X, Gao H, Lin Y, Yao Y, Zhu S, Wang J, Liu Y, Yao X, Meng G, Shen N, Shi Y, Iwakura Y, Qian Y^#. 2014. Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis. Immunity. 40 (1), 140-152. (IF=24)

13. W Pan, S Zhu, D Dai, J Harley, N Shen^#. 2014. Mir-125a Is Critical Regulator for Controlling Autoimmunity in Multiple Autoimmune Diseases through Stabilizing Treg Mediated Immune Homeostasis.Arthritis & Rheumatology.66():S1245, OCT 2014. (IF=8)

2013

12. Zhu S^#, Pan W, Qian Y^#. 2013. MicroRNA in immunity and autoimmunity. J Mol Med. Sep;91(9):1039-50. doi: 10.1007/s00109-013-1043-z. (^#co-corresponding author; Invited review)(IF=5)

11. Cao J, Zhu S, Zhou W, Li J, Liu C, Xuan H, Yan J, Zheng L, Zhou L, Yu J, Chen G, Huang Y, Yu Z, Feng L^#. 2013. PLZF Mediates the PTEN/AKT/FOXO3a Signaling in Suppression of Prostate Tumorigenesis. PLoS One. 8 (12), e77922. (IF=4)

2012

10. Zhu, S.*, W. Pan*, X. Song, Y. Liu, Y. Tang, H. Wang, W. Liu, Y. Shi, D. He, J.B. Harley, N. Shen and Y. Qian^#. 2012. The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α. Nature Medicine. 18: 1077-1086. DOI 10.1038/nm.2815. (Comment in Nature Reviews Immunology (2012) 474-475; Comment in Nature Medicine (2012) 18, 1009–1010; Evaluated by Faculty of 1000 Biology. *co-first author).(IF=33)

9. Zhu, S. & Qian, Y^#. 2012. IL-17/IL-17 receptor system in autoimmune disease: mechanisms and therapeutic potential. Clin Sci (Lond) 122, 487-511. (Invited review)(IF=5)

8. Yao Y., Y. Wang, F. Chen, Y. Huang, S. Zhu, Q. Leng, H. Wang, Y. Shi, Y. Qian^#. 2012. NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogen. Cell Research. 04/2012;(IF=15)

7. Qu F, Gao H, Zhu S, Shi P, Zhang Y, Liu Y, Jallal B, Yao Y, Shi Y, Qian Y^#. 2012. TRAF6-Dependent Act1 Phosphorylation by the I kappa B Kinase-Related Kinases Suppresses Interleukin-17-Induced NF-kappa B Activation. Mol Cell Biol 32: 3925-3937.(IF=4)

2011

6. Song, X., S. Zhu, P. Shi, Y. Liu, Y. Shi, S.D. Levin, and Y. Qian^#. 2011. IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens. Nature Immunology. 12:1151-8.(IF=22)

5. Shi, P., S. Zhu, Y. Lin, Y. Liu, Z. Chen, Y. Shi, and Y. Qian^#. 2011. Persistent stimulation with interleukin-17 desensitizes cells through SCFbeta-TrCP-mediated degradation of Act1. Science Signaling. 4:ra73.(IF=7)

4. Shi P, Zhu S and Y Qian^#. 2011. IL-17 mediated signaling and function. Chin J Cell Bio. 2011, 33(4): 345-357. (Invited review)

2010

3. Zhu, S., W. Pan, P. Shi, H. Gao, F. Zhao, X. Song, Y. Liu, L. Zhao, X. Li, Y. Shi, and Y. Qian^#. 2010. Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling. J Exp Med. 207:2647-2662. (Research highlight in Nature Medicine (2011) 17:52; Research highlight in Nature Immunology (2011) 12:19; Evaluated by Faculty of 1000 Biology).(IF=15)

2. Pan, W*, S. Zhu*, M. Yuan, H. Cui, L. Wang, X. Luo, J. Li, H. Zhou, Y. Tang, and N. Shen^#. 2010. MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol. 184:6773-6781.(*co-first author; 331 citations)(IF=5)

2009

1. Yu, Z., P. Ji, J. Cao, S. Zhu, Y. Li, L. Zheng, X. Chen, and L. Feng^#. 2009. Dazl promotes germ cell differentiation from embryonic stem cells. J Mol Cell Biol. 1:93-103.(IF=6)

｜专利

1. Inventors: Youcun Qian, Nan Shen, Shu Zhu, Wen Pan. “The application of microRNA in autoimmune diseases”. China Patent Application. 2012101174656

2. Inventors: John B. Harley, Nan Shen, Wen Pan, Shu Zhu. “Manipulating the Activity of miR-125a to Modulate Inflammation”.

｜所获奖励

2006年郭沫若奖学金（中国科学技术大学本科生最高荣誉）

2011年中科院院长优秀奖

2011年强生亚洲优秀研究生论文奖

2012年中科院院长特别奖（中国科学院研究生最高荣誉）

2012年吴瑞奖学金（大中华地区生命科学研究生最高荣誉）

2012年中科院百篇优博论文（中国科学院博士毕业生最高荣誉）

2014年Helen-Hay Whitney-HHMI Fellowship（美国最为著名的奖学金之一）

2017年中组部青年创新人才计划

2018年MIT Technology Review 35 Innovators Under 35（MIT TR35 China）

2018年求是杰出青年学者（每年授予十个左右中国top10高校最优秀的青年学者）

2018年基金委优青

｜组织会议,大会报告及学术交流：

10/2019特邀报告，Intestinal Immune- Enteric Virus Interaction in Health and Disease，西湖大学

07/2019特邀报告，功能微生物筛选及免疫机制，先声药业，上海

05/2019共同主席，中国肠道大会；共同主席（with EranElinav），肠道微生物与人体健康分会场；北京

03/2019特邀报告，Intestinal Immune- Microbes Interaction in Health and Disease，罗氏中国，上海

12/2018特邀报告，Intestinal Immune- Microbes Interaction in Health and Disease，北京大学

12/2018大会报告，Intestinal Immune- Microbes Interaction in Health and Disease，上海炎症性肠病论坛, 上海

10/2018大会报告，Intestinal Immune-Enteric Virus Interaction in Health and Disease，The 6th International Conference for Cellular Dynamics & Chemical Biology, 安徽

10/2018特邀报告，Intestinal Immune- Microbes Interaction in Health and Disease，复旦大学

10/2018大会报告，Intestinal Immune- Microbes Interaction in Health and Disease，第二届益生菌、肠道微生物与人体健康国际研讨会，江苏无锡

09/2018大会报告，Intestinal Immune-Enteric Virus Interaction in Health and Disease，2018年度中国细胞生物学学会免疫细胞生物学分会年会，浙江大学

08/2018大会报告，Intestinal Immune-Enteric Virus Interaction in Health and Disease，第七届哈纳斯论坛：科学与艺术，新疆

06/2018共同主席（with杨辉），第二届吴瑞青年论坛，安徽

05/2018特邀报告，Intestinal Immune- Microbes Interaction in Health and Disease，中科院微生物研究所，北京

05/2018特邀报告，Intestinal Immune- Microbes Interaction in Health and Disease，中科院神经生物学研究所，上海

11/2017大会报告, Intestinal Immune- Microbes Interaction in IBD, 上海炎症性肠病论坛, 上海

11/2017大会报告, 病毒组与人体健康和疾病, 2017年人体微生物组与健康学术年会, 北京

10/2017大会报告, Intestinal Immune- Microbes Interaction in Health and Disease, 第一届吴瑞青年论坛，北京

10/2017大会报告, Intestinal Immune- Microbes Interaction in Health and Disease, 第十四届长三角科技论坛—微生物组学的科学研究与转化，上海

07/2017大会报告, NOD-Like Receptors:  Guardians of Intestinal Mucosal Barriers, 第18届国际黏膜免疫大会 (ICMI 2017), 美国华盛顿DC

11/2016大会报告, NOD-Like Receptors:  Guardians of Intestinal Mucosal Barriers, Helen Hay Whitney Foundation Annual Symposium, MIT, MA